The drug "Lozartan": instructions for use

The drug "Losartan potassium" belongs to the category of antihypertensive drugs. Synonymous with medications are medicines "Lorist", "Cosaar".

Characterizing the drug "Losartan", instructionindicates its ability to reduce peripheral vascular resistance, the content of aldosterone and norepinephrine in the blood, pressure in a small circle. The drug also has a diuretic effect. The drug "Losartan" prevents the development of hypertrophy in the myocardium, increases the tolerance of patients to exercise on the background of heart failure in a chronic form.

A single dose of the drug causes a maximumhypotensive effect after six hours. During the day, the effect gradually decreases. The most stable hypotensive effect is observed after three to six weeks from the beginning of treatment.

The drug "Losartan" (reviews of experts point to this) reduces by one third the risk of hospitalization for exacerbations of chronic heart failure.

The drug is prescribed forarterial hypertension (increased pressure of a persistent nature). The tool "Lozartan" instruction recommends taking in order to reduce the likelihood of cardiovascular disease and death in patients with left ventricular hypertrophy and hypertension. Also, the drug is indicated in patients with diabetes mellitus of the second degree with proteinuria and with heart failure in chronic form with no therapeutic effect on the use of ACE inhibitors.

The drug "Losartan" instruction recommends taking inside a day once, regardless of food intake.

Daily dosage for hypertension,with diabetes mellitus of the second degree - 50 mg. This amount (if necessary and on the advice of a doctor) can be doubled. In this case, it is recommended to divide the dosage into two doses.

If the patient takes diuretics in high doses, the amount of the drug "Losartan" should be reduced to 25 mg per day.

For patients suffering from liver and kidney pathologies, lower doses of the drug are indicated.

In the presence of chronic heart failureThe initial dosage of the drug "Losartan" is 12.5 mg per day. Usually, the increase in dosage is doubled at an interval of one week (12.5 mg, then 25 mg, then 50 mg).

To reduce the risk of cardiovascular pathologiesand lethal outcome with hypertrophy in the left ventricle and chronic heart failure, the initial amount of the drug "Losartan" - 50 mg once a day. Further, it is recommended to increase the dosage in half (without changing the number of doses) or additional administration of hydrochlorothiazide.

To contra-indications to a medicine "Losartan"the instruction refers to hypersensitivity, children's age (up to eighteen years). No medication is given to pregnant or lactating women. If found in a patient during pregnancy treatment, the drug must be immediately discontinued.

Caution should be given to patients with arterial hypothesis, dehydration, hyperkalemia, hepatic or renal insufficiency.

When you receive funds "Lozartan" are possibledizziness, insomnia, increased fatigue, rhinitis, bronchitis, dyspnea, the occurrence of infections in the upper respiratory tract. The use of the medicine can provoke abdominal pain, constipation, nausea, flatulence, vomiting, and an upset of appetite. There may also be pain in the back, legs, chest, cramps, fibromyalgia and other conditions.

Before using the drug, you should consult a doctor, carefully read the annotation.