Medication "Ginepristone". Reviews, description, application
The drug "Ginepristone" belongs to the categorysynthetic steroidal anti-gestagenic agents. The drug is able to block the activity of progesterone. The drug enhances the ability to reduce myometrium, stimulates the release of interleukin-8 in chorio-decidual cells, increasing the sensitivity of the myometrium to prostaglandins. The drug "Ginepristone" (the doctors' testimonies confirm this), depending on the phase of the menstruation cycle, can cause a slowdown in ovulation, changes in the endometrium, and prevent the implantation of a fertilized egg.
At a single admission, the maximum concentrationis observed after 1.3 hours. The drug is almost completely (98%) associated with plasma proteins. Removal of the medicine from the body is carried out in two phases.
Medication "Ginepriston" instruction recommendstake for urgent postcoital contraception. The drug is used after unprotected sexual intercourse or in case of unreliability of the contraceptive used.
Medication "Ginepriston" (reviews of specialistsindicate it) should be taken within seventy-two hours after intercourse. The drug is taken once in a dose of ten milligrams of active ingredient (one tablet).
In order to maintain contraceptive effectiveness, it is recommended to refrain from eating two hours before and after using the medication.
The drug "Ginepristone" (expert reviews are unambiguous in this) can be taken at any phase of the menstruation cycle.
In some cases, when using a medicamentthere is vomiting, nausea, dizziness, headache. Sometimes the drug "Ginepristone" (the patient's testimonies confirm this) provokes a cycle disorder, causes bloody discharge from the vagina. In some cases, there may be an allergy, a feeling of discomfort in the lower abdomen, hyperthermia, weakness.
The drug "Ginepriston" (reviews of specialistsunambiguous in this) is not prescribed for renal and hepatic insufficiency (both acute and chronic), in the presence of extragenital pathology of severe course, adrenal insufficiency. Contraindications include long-term use of glucocorticosteroids, hypersensitivity.
Caution is recommended whenappointment to patients with hemostasis disorders, obstructive pathologies in the lungs of the chronic course, bronchial asthma, cardiac arrhythmias or heart failure, and hypertension in severe conditions.
The drug "Ginepristone" is contraindicated in pregnancy. After applying the medicine during lactation, a woman should stop feeding for fourteen days.
It should be noted that the drug "Ginepristone"It is not prescribed and is not used as a planned continuous contraceptive. The medication does not provide protection against infections transmitted through sexual contact.
Specialists do not recommend the use of the drug "Ginepristone" in conjunction with anti-inflammatory non-steroid drugs.
Unwanted effects do not occur when using the medication at the recommended dosage. When taking medication in large quantities, adrenal insufficiency may occur.
According to some experts, the drug"Ginepristone" is considered to be quite effective in providing emergency contraception. Comments of many patients confirm the high effectiveness of the medication.
Before using the drug "Ginepristone" you need to consult a doctor and carefully study the instructions.