Pirentel - instructions for use.
Dosage form
The drug is available in two dosage forms - tablets and suspensions.
The capsule pills are yellow and risk on one side.
Composition:
Active substance:
- pyrantel pamoate 250 mg (in 1 table).
Excipients:
- arabic gum;
- gelatin;
- starch;
- propylparaben;
- methylparaben;
- talc;
- colloidal silicon dioxide;
- magnesium stearate;
- sodium glucose starch.
Pyrantel - suspension. Instructions for use include the type and composition of the suspension. Suspension is also yellow, viscous.
Composition:
Active substance:
- pyrantel pamoate - 50 mg (in 1 ml of suspension).
Excipients:
- saccharin sodium;
- sodium methyl paraben;
- sucrose;
- sodium propylparaben;
- sodium chloride;
- sorbitol 70%;
- sodium carboxymethylcellulose;
- polysorbate 80;
- purified water;
- chocolate chips.
Pharmacological action of the drug "Pirantel"
The instruction says that "Pirantel" is a drug,belonging to the group of anthelmintic means. The drug can cause a neuromuscular blockade against sensitive helminths. The drug is more active in relation to Necator americanus, Ancylostoma duodenale, Enterobius vermicalaris, less active against Nrichocephalus trichiurus.
The drug, thanks to its action, is capable ofaffect all age groups of parasites - that is, both on immature individuals and sexually mature, in addition, it affects individuals of any gender. But the drug can not have any effect on the larvae of individuals, especially those that are in the migration stage.
Pharmacokinetics
The drug after consumption is almost nonexistentabsorbed from the digestive tract. The maximum concentration of the drug in the blood after a single dose is reached after 1-3 hours. Pirantel is metabolized to its metabolites in the liver and almost unchanged is excreted from the body, mostly through the intestine (93%). Another 7% can be excreted by the kidneys in the form of metabolites or simply unchanged.
Indications for the use of the drug "Pirantel"
The instruction includes 4 types of disease, in which there is a need for taking this medicine.
- trichocephalus;
- necropsy;
- ankylostomidosis;
- ascaridosis.
Dosage of the preparation "Pirantel", applicationwhich must be performed only after a meal, should be installed by the doctor, based on the patient's age data, weight, as well as contraindications and the possibility of side effects.
When treating enterobiasis should be treatedsimultaneously all persons living on one living space. This measure is aimed at excluding the possibility of re-infection, for example, from one of the family members. After treatment, it is necessary to make tests to check the presence of parasites in the patient's body.
Side effects
Possible side effects of the drug on the part of the digestive tract:
- diarrhea;
- nausea;
- anorexia;
- vomiting;
- increase in liver transaminase activity.
Possible side effects of the drug from the peripheral and central nervous system:
- hallucinations;
- headache;
- dizziness;
- confusion of consciousness;
- insomnia;
- drowsiness.
Other side effects:
- temperature increase;
- skin rash.
Contraindications to the preparation of pyrantel
Instructions for the medication include only the main contraindications to the drug:
- myasthenia gravis;
- sensitivity to pyrantel;
- pregnancy;
- lactation.
The drug should be used with caution in liver failure in a patient's history.
Do not administer laxatives after taking the drug.
Children under 6 years of age, this drug is administered with great care.
Drug interaction of the drug "Pirantel"
The instruction says that when applying pyrantel simultaneously with piperazine, the effect of the second is noticeably weakened.
