"Meloksikam" preparation: instructions for the use of injections and suppositories
The drug "Meloxicam" refers topharmacological group Oksikama, has anti-inflammatory, analgesic, antipyretic effect. This medication is available in three forms: an intravenous solution, suppositories and tablets. This article is devoted to the description and instructions for the use of the drug "Meloksikam" in the form of a solution for injection and in the form of suppositories (suppositories).
Composition of the preparation and form of release
"Meloksikam" -schools-rr for introduction in / m: 1 ampoule contains the active substance meloxicam 15 mg and additional substances in the composition: meglumine, glycofurol, poloxamer 188, sodium chloride; glycine; sodium hydroxide; water for injection. The ampoule is divided into 1.5 ml ampoules, the contourcell pack contains 3 or 5 ampoules; a pack of cardboard holds 1 package. The solution is yellow, with a green tint, transparent.
"Meloksikam" candles - 1 candle (suppository)contains active substance meloxicam - 7.5 mg and additional substances in the composition: suppository mass (suppocira BP), macrogol glyceryl hydroxy stearate. The contourcell can contain 6 pieces; in a box of cardboard - 1 or 2 cell packs. Candles - the surface is smooth, yellowish with a green tinge, with a depression in the base.
Pharmacological action of the preparation "Meloxicam"
The instruction defines it as a means with anti-inflammatory, analgesic and antipyretic effects.
Pharmacodynamics
The drug "Meloksikam" is an NSAID, it isa derivative of enolic acid and has anti-inflammatory, analgesic and antipyretic effects. The mechanism of anti-inflammatory action of the drug is its ability to suppress the synthesis of PG, which are mediators of inflammation.
Indications for the use of the drug "Meloksikam"
Mortar for injections "Meloksikam" instructionprescribes the use of this form in the initial period of pain therapy and not for long, in symptomatic therapy for rheumatoid arthritis, osteoarthritis, ankylosing spondylitis.
Candles "Meloksikam" used in symptomatic treatment for osteoarthritis (arthrosis, degenerative joint diseases); ankylosing spondylitis; rheumatoid arthritis.
General contraindications to the use of medication "Meloxicam"
The instruction does not allow the use of the drugwith increased sensitivity to the components of the drug; symptoms of bronchial asthma; polyps of the nose; angioneurotic edema or urticaria caused by taking an acetylsalicylic acid or other NSAID in an anamnesis; ulcer disease in the acute stage or recently transferred.
It is also forbidden to apply the drug in case of illnessCrohn's or ulcerative colitis in the stage of exacerbation; severe hepatic and renal insufficiency; acute gastrointestinal bleeding, recent cerebrovascular bleeding, or an established diagnosis of diseases causing abnormalities in the blood coagulation system; severe uncontrolled heart failure; pregnancy; breastfeeding; therapy of perioperative pain during shunting of the coronary arteries.
Additional contraindications for injections: It is prohibited to use in children under 18 years of age. Additional contraindications for suppositories: in children under 12 years, the exception is the use in the case of juvenile rheumatoid arthritis.
Side effects when using the drug "Meloxicam"
The instruction warns of possible side effects in the organs of hematopoiesis in the form of a change in the formula of blood cells.
In the immune system in the form of anaphylactic shock,anaphylactic reactions. In the central nervous system in the form of headache, confusion, disorientation. In the gastrointestinal tract as a perforation of the gastrointestinal tract, gastrointestinal bleeding, etc.
In the skin and skin appendages in the form of epidermal toxic necrolysis, Stevens-Johnson syndrome, angioedema, etc.
In the respiratory system in the form of bronchial asthma. In the CAS in the form of increased blood pressure, palpitations, a surge of blood to the face, edema.
In the genitourinary system manifestations of acute renal failure, changes in kidney function.
In the organs of vision in the form of conjunctivitis, visual impairment.
Interaction
Simultaneous use with other NSAIDs is not recommended.
Overdose
Information is not enough.
Method of application of the drug "Meloxicam"
Injections are done only in the first days of therapy (2-3days). Then the treatment is continued with enteral forms. The recommended dose of the injection is 7.5 mg or twice as much as -15 mg, administered once a day. The recommended daily maximum dose is 15 mg. The medication is administered deep in the / m. Rectal suppositories are recommended to be used in a dose of 7.5 mg once a day. In some cases, you can increase the dose twice.
