Medication "Arifon". Instructions for use
The drug "Arifon" (reviews of patients for thisindicate) is very effective in the initial manifestations of hypertension. The advantages of the medication include a mild diuretic effect, mild antihypertensive effect.
The active component of the drug, indapamide, is close(on pharmacological properties) to thiazide diuretics. The active substance helps to enhance the excretion of urine ions of chlorine and sodium, as well as magnesium and potassium (to a lesser extent). This is accompanied by an increase in diuresis. Antihypertensive effect is noted in dosages that do not have a pronounced diuretic effect. The hypotensive effect of the drug is related to the properties of indapamide to lower the overall peripheral vascular resistance and to increase the elasticity of arterial walls.
The "Arifon" means helps to reduce hypertrophy in the left ventricle of the heart.
As a result of clinical studiesIt is established that monotherapy with the drug provokes a persistent hypothetical effect. The effect lasts for twenty-four hours and is accompanied by a moderate increase in diuresis.
Medication "Arifon". Instructions for use. Appointment
The drug is indicated for hypertension (elevated blood pressure).
It is advisable to take the preparation inside by a pill a day, preferably in the morning.
To adverse manifestations of the means "Arifon"The instructions for use refer to the development of hypokalemia (especially in patients prone to a decrease in potassium concentration). In addition, taking medication can provoke hyponatremia, complicated by hypovolemia, orthostatic hypertension and dehydration of the body.
Very rarely there is an increase in the concentration of calcium in the blood.
To adverse manifestations of the medication "Arifon"The instruction refers to allergic reactions, hemorrhagic vasculitis (in rare cases), dry mouth, constipation, agranulocytosis, hemolytic anemia, leukopenia, asthenia, thrombocytopenia, paresthesia (numbness).
Taking the drug may also cause headache or dizziness. These and other reactions from the nervous system (central and peripheral), as a rule, are eliminated when the dosage is lowered.
In the presence of liver failure on the background of the use of the "Arifon" means the development of hepatic encephalopathy is possible.
As experts note, most of the negative reactions are dose-dependent.
Medication "Arifon". Instructions for use. Contraindications
Not recommended medication for hypokalemia, renal failure, hepatic encephalopathy, individual intolerance.
Medication "Arifon" instructions for use are notAllows to accept at pregnancy (for elimination of physiological edemas, including). Diuretics can cause fetoplacental ischemia and provoke abnormalities in fetal development.
It is established that indapamide is excreted with milk. In this regard, the appointment of the drug "Arifon" during lactemia is contraindicated.
special instructions
When prescribing Arifon for diabetes mellitus, it is necessary to systematically monitor the concentration of glucose in the blood, especially against the background of hypokalemia.
In patients with a high concentration of uric acid, there is a predisposition to an increase in the number of gout attacks.
With the development of hepatic encephalopathy in patients with liver failure, the drug should be immediately withdrawn.
It must be remembered that hypokalemia contributes todevelopment of cardiac arrhythmias. In this regard, it is necessary to systematically determine the concentration in the blood plasma of potassium ions. When hypokalemia occurs, appropriate therapy is prescribed.
Before using the drug "Arifon" you should read the annotation.
