Medicinal product "Trimedat". Instructions for use
Medicinal product "Trimedat" instructions forapplication refers to the group of antispasmodics. It is produced in the form of tablets, each containing two hundred milligrams of tri -butine maleate, the main active ingredient. Among the auxiliary components are: corn starch, talc, lactose, colloidal silicon dioxide, magnesium stearate.
Tablets are painted white, their shape is round, biconvex, on one side there is a risk.
Active active substance of the drug -trimebutin - regulates peristalsis of the intestine, affecting its enkephalinergic system. This component also acts as a stimulant in the case of hypokinetic states of the smooth muscles of the intestine, and spasmolytic - in hyperkinetic.
The drug "Trimedat", the instruction informs,exerts its influence on the entire gastrointestinal tract, reduces pressure on the sphincter of the esophagus. The medication also favors the activation of intestinal peristalsis and promotes the rapid painless emptying of the stomach.
Trimebutin is able to restore the normal natural activity of the musculature of the intestine for various diseases localized in the digestive tract, which are associated with malfunctions in motor activity.
The maximum content of the drug in the bloodis achieved after one or two hours after oral administration. Bioavailability fluctuates within four to six percent. It is noted that the active ingredient of the medicament is able to penetrate insignificantly through the fetoplacental barrier.
Trimebutin undergoes the biotransformation process inliver, is excreted together with urine, mainly in the form of metabolites (with seventy percent of them leaving the body during the first day). The half-life is twelve hours.
The medicine "Trimedat" is indicated for use in the following cases:
- with motor disorders accompanying functional gastrointestinal diseases;
- for the treatment of gastroesophageal reflux disease;
- in dyspeptic disorders that are symptoms of gastroduodenal diseases;
- for the treatment of irritable bowel syndrome,It is a functional disease of the gastrointestinal tract, accompanied by cramps, colic and abdominal discomfort, abdominal distention, and abnormal stools;
- with paralytic intestinal obstruction after surgery;
- in preparation for endoscopic or radiographic studies of the stomach.
Tablets "Trimedat" for children are used for dyspeptic disorders caused by the violation of the gastrointestinal tract.
Considered pharmaceutical agentcontraindicated in case of hypersensitivity to substances in its composition. In addition, the drug in this dosage form is not prescribed to patients under twelve years of age.
The drug "Trimedat" (instruction draws thisspecial attention) should not be used for therapeutic purposes in the first trimester of pregnancy. In addition, he is not appointed during the entire period of breastfeeding, since there is no reliable clinical information confirming the safety of taking the medication during this period.
Medicinal product "Trimedat". Instructions for use
The drug is taken orally for one or two to two milligrams three times during the day.
Among the side effects that manifest themselves against the background of the use of this drug, emit allergic reactions (are extremely rare).
The shelf life of the drug is thirty-six months.
