"Tenorik": reviews of doctors. Tablets from high blood pressure

Is such a drug as "Tenorik" effective? Everyone can leave a comment about this drug. Thanks to such reports, both doctors and patients can easily draw a conclusion about how the medicament works, whether it causes side reactions and whether it cope with the task.

In this article, we will describe in detail the properties and characteristics of the preparation "Tenorik". The recall of the patient who receives it as prescribed by the doctor will also be presented below.

Composition, form, description, packaging

The preparation "Tenorik" (100, 50 mg) goes on sale in the form of white tablets with a round and biconcave form with a dividing risk.

The composition of this medicine includes two activecomponent: chlorthalidone and atenolol. Also this preparation contains additional components, which are presented in the form of corn starch, sodium lauryl sulfate, lactose, polyvinylpyrrolidone, talc, silicon dioxide, isopropanol and magnesium stearate.

One can not help saying that the tablets "Tenorik"(you can see the tip about this tool at the end of the article) covered with a special film shell. It consists of methylene chloride, isopropanol, talc, hypromellose, titanium dioxide, macrogol and vaseline oil.

You can buy this drug in blisters or strips of 100 or 28 tablets.

Pharmacology of medicament

What are tablets "Tenorik"? Instructions for use (the price of the drug is not very high) reports that it is an antihypertensive combination that can have a prolonged hypotensive effect.

The effectiveness of the drug in question is due to the action of 2 components, or rather the diuretic (chlorthalidone) and beta1-adrenoblocker (atenolol).

Basic properties

Atenolol is called cardioselectivebeta1-adrenoblocker. The selective ability of this substance decreases with increasing dosage of the drug. Atenol does not have internal membrane-stabilizing and sympathomimetic effects. As well as other beta-blockers, it has a negative inotropic effect and significantly reduces heart rate.

As for chlortalidone, it is a diuretic(sulfonamide non-iazide). It enhances the isolation of elements such as chlorine and sodium. Also, this component increases the release of bicarbonate, magnesium and potassium. The principle of its antihypertensive action is associated with the excretion of sodium.

The combination of atenolol with diuretics is more effective than using each of these components separately.

The effect of the medicament in question is maintained throughout the day (after a single dose in a daily dosage).

Kinetics of the drug

In view of the fact that the preparation "Tenorik", analogues, the price of which is presented below, is a combined means, we will consider the kinetic properties of each of the active substances separately.

Atenolol is absorbed on 40-50% of the gastrointestinal tract. Its maximum concentration is reached 4 hours after taking the tablet. The connection with proteins is approximately 8-16%.

Atenolol is not strongly pronouncedmetabolism in the liver. About 90% of the absorbed substance is excreted unchanged for 8-9 hours. This period can be increased with severe renal failure, since atenolol is excreted by the kidneys.

As for chlortalidone, it is absorbed 60% from the digestive tract. In plasma, its maximum concentration is reached after 12 hours. The connection with proteins is approximately 75%.

Chlorthalidone is excreted by the kidneys for 50 hours.

Indications for use

The above drug helps very well from high blood pressure. Actually, hypertension is the main and, perhaps, the only indication for use.

Contraindications

Now you know what the purpose might beTablets "Tenorik" were prescribed (the indications for taking this medication were presented above). But, unfortunately, the medication in question also has a rather impressive list of contraindications. It is not recommended to take when:

shock cardiogenic;
pheochromocytoma;
bradycardia (pronounced seizures);
severe violations in the peripheral circulation;
arterial hypotension (progressive and severe);
metabolic acidosis;
AV-blockade of the 1st and 3rd degree;
SSSU;
bronchial asthma progressing;
cardiac insufficiency (both acute and chronic);
diabetes mellitus;
angina of the vasospastic (Prinzmetal stenocardia);
gout;
obstructive bronchitis;
acute hepatitis;
hypoglycemia;
renal failure in acute form;
under the age of 18;
myasthenia gravis;
hypersensitivity to the ingredients of the drug.

How to take "Tenorik" from high blood pressure?

Adult patients are recommended to take this medication in an average dosage of 100 mg. In this case, the initial dose of the drug should be 50 mg once a day.

As for the elderly, the drug "Tenorik" they are appointed in even smaller quantities.

Patients with impaired renal function are advised to reduce the frequency of taking tablets.

It should also be noted that after long-term use of the drug in question, its cancellation is required to be carried out gradually.

Side effects

Receiving tablets "Tenorik" can provoke the appearance of the following adverse reactions:

bradycardia, increased signs of heart failure, cold extremities, orthostatic hypotension, arrhythmia, AV blockade, symptoms of intermittent claudication, Raynaud's syndrome;
confusion, apathy, headaches, hallucinations, acute psychosis, paresthesia, mood swings, dizziness, fatigue, sleep disturbance, disorientation, visual impairment;
dry mouth, increased hepatic transaminases, gastrointestinal disorders, hepatotoxicity with intrahepatic cholestasis, pancreatitis, nausea, constipation, anorexia;
leukopenia, purpura, thrombocytopenia, eosinophilia, agranulocytosis;
alopecia, psoriasis-like reactions, dry eyes, exacerbation of psoriasis, photosensitivity, skin rash;
bronchospasm, hyperuricemia, hypokalemia, hyponatremia;
a violation of glucose tolerance, an increase in the number of antinuclear antibodies, a decrease in potency.

The listed side effects are extremely rare and poorly expressed.

Price, analogues

The cost of "Tenorik" tablets is 110-120 rubles. You can replace them with drugs such as "Athenol", "Dinoric" or "Tenoret".

Reviews about the medicine "Tenorik"

A feedback on the effectiveness of this tool can leave everyone. According to patients and doctors, the main advantages of this remedy are:

efficiency;
low cost.

Among the shortcomings of this drug include:

the probability of hair loss and the development of impotence (with long-term treatment);
the likelihood of seizures.