Diacarb, instruction for use, side effects, contraindications

"Diacarb" is released in the form of tablets. The active substance of the drug is acetazolamide (250 mg in 1 tablet), which belongs to the group of diuretic drugs.

Pharmacological action "Diakarba" is based onability to inhibit carbonic anhydrase. Acetazolamide has a diuretic effect, increases the excretion of urine ions (sodium, potassium, bicarbonate). "Diacarb", the instruction indicates, does not affect the amount of chloride ions in the urine, shifts the urinary pH level upwards. The metabolic acidosis depends on the concentration of acetazolamide in the body. By inhibiting the carbonic anhydrase, "Diacarb" reduces the release of watery moisture, lowers the intraocular pressure. An anticonvulsant effect of the drug has, suppressing the activity of carbonic anhydrase directly in the brain.

"Diacarb", the instruction indicates, is digestederythrocytes, kidneys, muscles, eyeball tissues, central nervous system. In the process of metabolism, the active substance reacts with plasma proteins and has a penetrating ability through the placenta.

Independently in the body, acetazolamide is not formed.

Diacarb, indications for use

The drug is prescribed:

with edematous syndrome, with mild or moderate degree of severity, with alkalosis;

with glaucoma in the primary or secondary form, during an acute attack;

with epilepsy "Diakarb" is introduced into the complex therapy;

with mountain sickness.

The dosage of the drug is determined by the doctor depending on the condition of the patient and the type of disease.

Diacarb, instruction for side effects

The central and peripheral nervous system inin rare cases, responds to the drug with the appearance of convulsions, paresthesias, tinnitus, nearsightedness; As a result of prolonged use, occasional cases of disorientation, disturbances in touch, drowsiness were observed.

In the work of the hematopoiesis system, changes occurred in single cases as a result of prolonged use, which were manifested by hemolytic anemia, leukopenia, agranulocytosis.

Possible disturbance of water-electrolyte metabolism, acid-alkaline environment, expressed: hypokalemia, metabolic acidosis.

"Diakarb", the use of which is longcharacter, can provoke in isolated cases a disruption in the work of the urinary system, which manifests itself in nephrolithiasis, transient hematuria and glucosuria.

The digestive system is sometimes at risk of anorexia, and with prolonged use, patients complain of nausea, vomiting, and diarrhea.

Dermatological allergic reactions are manifested by skin flushing, itching, hives.

In some cases, muscle weakness developed.

Diacarb, instruction for contraindications

It is forbidden to prescribe the drug:

with acute renal failure;

hepatic insufficiency;

hypokalemia;

acidosis;

hypokorticism;

Addison's disease;

uremia;

diabetes mellitus;

pregnancy;

in the lactation period;

with increased sensitivity to one of the components of the drug.

Assign "Diakarb" for swelling of the liver andnephritic origin should be cautious. Close monitoring of the attending physician is necessary when acetazolamide is combined with acetylsalicylic acid in high concentration.

"Diacarb", the instruction indicates, has specific instructions for the appointment. If the drug in the treatment of the patient is used for more than five days, then there is a risk of metabolic acidosis.

Assigning the drug a long course of treatment, you need to monitor the analysis of peripheral blood, indicators of water-electrolyte metabolism, the equilibrium of acid-alkaline environment.

"Diacarb", used in high doses, causessigns of drowsiness, fatigue, dizziness and disorientation. Therefore, during the period of treatment, patients are not advised to operate machinery and transport.