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If you have bilirubin

Bilirubin is a bile pigment thatis contained in the blood of each person and is excreted along with bile through the biliary tract. It is formed daily as a result of the breakdown of the hemoglobin protein, but its content in the blood rises only if this disintegration becomes pathological. If you have increased bilirubin, this may indicate the presence of serious diseases.

The mechanism of increased bilirubin

In erythrocytes, the protein contains hemoglobin,thanks to which red blood cells transfer oxygen to all organs and tissues. Old and incompetent erythrocytes are destroyed in the spleen, liver and bone marrow, while releasing the altered hemoglobin, which can be transformed into direct and indirect bilirubin. Indirect bilirubin is toxic, therefore it is immediately neutralized by liver enzymes, and the direct bile is excreted along with bile naturally.

The content of bilirubin in the blood is determined fromusing biochemical analysis. To ensure an accurate result of the analysis, the patient is not recommended to eat for at least eight hours before it is handed over. In the blood, the normal content of bilirubin is considered to be 8.5 - 20 μmol / l, indirect - up to 4.2 μmol / l.

Do not engage in self-medication, in the event,if you have increased bilirubin. How to treat in this case the patient, should only decide the doctor. Before starting treatment, you need to find out the cause of increased bilirubin. There are a number of diseases in which bilirubin is elevated.

Diseases in which bilirubin is elevated

  • Jaundice

The liver is the organ that plays the main role inmetabolism of bilirubin, so in the case of viral hepatitis, the amount of bilirubin in the blood will increase markedly. In addition, with hepatitis, the skin begins to acquire a yellowish hue. The reason for this is the "unutilized" liver of bilirubin, which begins to penetrate into the tissues of the skin and other organs.

  • Anemia

Anemia is a lack of blood supply, that isdecrease in the total number of red blood cells. As already mentioned, when erythrocytes die, bilirubin is released. If it comes too much, then the liver enzymes just do not have time to process it. As a consequence, bilirubin is increased and accumulated, causing irreparable harm to the entire body.

Other factors in which bilirubin is elevated

  • Because of a violation of the outflow of bile

Outflow of bile may be impaired due to cancerpancreas, cholelithiasis, or other factors narrowing the biliary tract. Bilirubin, a high level of which is visually noticeable by the color of the skin, accumulates in the tissues. The patient has such symptoms as itchy skin, vomiting, belching, decreased appetite and even kidney colic.

  • During pregnancy

During pregnancy, bilirubin is elevated usuallyonly in the last trimester. For pregnant women it is especially important to determine the true causes of high bilirubin, otherwise it may have complications such as hepatitis, anemia or cholecystitis.

  • High bilirubin in newborns

At newborns the raised or increased level of a bilirubinis the norm, because after birth, the baby's red blood cells begin to actively degrade, while releasing fetal hemoglobin, which is necessary for normal fetal oxygenation. To sound an alarm is necessary only in the event that the physiological jaundice goes beyond the redistribution of the norm.

In any case, treat elevated bilirubinshould only the doctor, focusing on anamnesis, data from the results of tests and examination of the patient. Do not engage in self-medication, because only with a correct diagnosis and a complete treatment course can the level of bilirubin be normalized.

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