The drug "Acyclovir" (ointment): instruction
The drug "Acyclovir" (ointment), the instruction forwhich is used in front of you - a drug that is used to treat various infections of the mucous membranes, skin that are caused by the herpes simplex virus, shingles. The medication is also used as an integrated therapy for chicken pox. The drug "Acyclovir" (eye ointment) is used to treat severe complications of herpes, which can affect the organs of vision. The drug has a pronounced antiviral effect.
Medication "Acyclovir". Form of issue, composition
The medicinal substance is releasedmainly in the form of an ointment in tubes of aluminum, which are placed in packs of cardboard. One gram of the drug contains fifty milligrams of the active substance - acyclovir. Auxiliary substances of the drug are low molecular weight and high molecular weight polyethylene glycol.
Medication "Acyclovir" (ointment). Instruction: pharmacokinetics, pharmacodynamics
The drug with topical application is not capable ofpenetrate into the bloodstream, its concentration in this tissue is negligible (0.01 mmol / l). The mechanism of action of the main component consists in a competitive interaction with the active substances of the virus (transaminase). As a result, a phosphorylation reaction takes place, the result of which is the formation of acyclovir phosphates. They are built into the DNA of the virus and inhibit the processes of building up their genetic material. Such activity is manifested in relation to the herpes simplex virus, shingles, Epstein-Barr. The main substances of the drug prevent the formation of new morphological elements of the rash, reduce the likelihood of dissemination of the skin, visceral complications, accelerate the formation of crusts, contribute to the reduction of pain in acute phases of herpes zoster.
Medicinal product "Acyclovir" (ointment). Instruction: method of administration, dose
The drug is intended for external use onlyapplication. It should be applied to the hearth five times during the day, observing the interval of four hours. Therapy should begin with the appearance of the first signs of the disease (the first blisters, tension, itching). The course of treatment is ten days. Ointment is also applied to the areas that border on the affected skin with herpes.
Pharmaceutical means "Acyclovir" (ointment). Side effects, contraindications
The drug has the following side effects: itching, burning, soreness, local irritation of the mucous membrane, which disappears after drug withdrawal, as well as skin rash, peeling of individual parts of the skin (with prolonged use may develop vulvitis).
Among the main contraindications should be allocated increased sensitivity to individual components, the period of pregnancy, lactation.
The drug "Acyclovir" (ointment). Instruction: drug interactions, specific instructions
When taking a joint medication"Interferon" and "Atsiklovir" antiviral effect of the latter is significantly enhanced by the increase in the rate of metabolic processes in the affected cells.
Ointment should be applied in rubberized gloves to prevent the possibility of infection of other areas.
During lactation, pregnancy the drug shouldapply with extreme caution, but it is better to abandon its use altogether. The drug has no effect on the ability to control machinery, vehicles.
Medication "Acyclovir" (ointment). Instruction: symptoms of an overdose
When the dose of the drug is exceeded, characteristic clinical signs appear:
- headache;
- Shortness of breath;
- neurological disorders;
- vomiting, nausea;
- Disorder of renal function;
- diarrhea;
- convulsions;
- a coma.
To eliminate them, hemodialysis is necessary.
