Zelboraf: price, analogues. Where is cheaper to buy "vemurafenib"?
Tablets "Zelboraf" - is an antitumora drug that is an inhibitor (i.e., a substance that suppresses the formation processes) of serine-threonine kinase. This enzyme is known as a regulator of many cellular processes, including as a catalyst for the development of cancerous tumors.
Zelboraf is prescribed to patients suffering froman inoperable melanoma with a mutation in the BRAF gene, which causes the production of an activated protein. This drug was developed specifically to block this gene and is often successfully used as a monotherapy.
Where can I buy Zelboraf more cheaply?
It's no secret that drugs for treatmentoncological diseases are, unfortunately, very expensive. So, in Russia on "Zelboraf" the price keeps within the limits from 115 000 to 120 000 rbl. But what should a person do that can not put the proposed amount for the means that are vital to him? To help in this case will come a well-proven site , offering generics of famous brand products.
On the generic "Zelboraf" the price is much lower thanon a branded drug, but this is not related to poor quality! Both the composition and effectiveness of the means are similar. Just a well-known Indian company that bought the right to manufacture these antineoplastic tablets did not invest in development, research and advertising, which affected such a significant difference in value.
Dosage and administration of medication
Treatment with the described agent is necessarycarry out only under the supervision of a specialist. To assign the tablets "Zelboraf", the instruction to which is offered to your attention, a mandatory test is performed for the presence of the pathological gene BRAF V600.
The recommended dose is usually 960mg (this is 4 tables) at a time. Take the drug twice a day, regardless of the time of eating. Although prolonged use on an empty stomach and the first and second dose should be avoided.
You can not chew the tablets. Drink better with water.
If the next reception of Zelboraf tablets wasmissed for any reason, you can drink them later, but with an interval between meals of 4 hours or more. Take both doses immediately. If the next pill reception caused vomiting, then you should not drink them extra. Continue treatment as before.
Who is contraindicated with the drug
"Zelboraf" is not prescribed to patients who have certain contraindications to the use of the described drug. These include:
- patients suffering from a severe degree of renal and hepatic insufficiency;
- Patients with violations of water and electrolyte balance that can not be corrected;
- children and adolescents under the age of 18;
- pregnant women;
- nursing;
- suffering from the syndrome of an elongated QT interval;
- taking drugs that promote the extension of the interval.
Side effects
When treating with Zelboraf, the following side effects are most often observed:
- increased fatigue;
- nausea, upset of the chair;
- development of alopecia and papilloma of the skin;
- decreased appetite and weight;
- distortion of taste sensations;
- headache;
- dizziness;
- peripheral neuropathy;
- dry skin;
- increased sensitivity to ultraviolet radiation;
- pain in muscles and bones;
- peripheral edema.
All the listed manifestations must be reported to the attending physician in order to avoid undesirable consequences.
